Some experts affirm that whole apples have superior nutrient density, while others point out that juice or liquid forms can be more convenient. Although apple consumption has been associated with several positive health outcomes, fewer reports have documented whether apples consumed in different forms, like apple juice, pomace, cider, vinegar, and others, exert the same beneficial effects as whole fruits. Besides being very accessible, versatile, and inexpensive, apples have a high nutritional value and contain a wide variety of bioactive components, making them a fruit of interest. Since fruits do not have the same nutritional or energetic density, they are likely to have inequivalent properties, and thus it becomes relevant to investigate the contribution of specific fruits to disease prevention.Īpples are a good example of fruit that has caught the attention of researchers for several reasons. The protective effect of FAV consumption is likely due to their high content in nutrients, fibers, and phytochemical components, as well as their low energetic density. Many biologically active components in FAV can play a preventing role in the development of a various range of chronic diseases including cancer and neurodegenerative diseases, for which many studies have investigated the effect of different fruit supplementations on related markers such as Wnt signaling, mucosal proliferation and the neuronal response to working memory load conditions. However, the health benefits of FAV extend beyond their cardioprotective effects. This review suggests that, in 20 studies, apple juice consumed in moderation exerts positive effects on markers of cardiovascular disease risk (particularly on oxidative stress).ĭata from the scientific literature supporting that fruits and vegetables (FAV) consumption is beneficial for cardiovascular disease prevention are quite undisputed. Most of the documentation was found regarding oxidative stress, as well as observations with other parameters such as markers of inflammation, lipid profile, and diabetes. Overall, cloudy apple juice consumption was found to be associated with several markers of cardiovascular health that may ultimately be relevant for cancer and neurodegenerative diseases. Of the 67 studies retained, 20 interventional studies on humans were reviewed. The present review aims to summarize the current literature on health benefits of apple juice as reported in clinical trials in humans. Juice consumption may be a convenient way to take advantage of the health effects of the bioactive components present in apples. Although numerous studies have reported the benefits of apple consumption on cardiometabolic health parameters and chronic disease prevention, few have focused on the effects of apple juice specifically.
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